Light Treatment Effectiveness Study

Joel M Gelfand

The LITE Study is a large pragmatic randomized study to compare the effectiveness, safety (tolerability), and duration of treatment response at 12 weeks of home versus office-based narrowband ultraviolet B phototherapy for the treatment of plaque or guttate psoriasis. 
The study’s design differs from a clinical trial in that it aims to reflect real world practice. LITE is guided by committee representatives of dermatology experts, patients with psoriasis, and leaders in health care insurance. The study hopes to narrow the gap in knowledge for patients, dermatologists, and healthcare plan payers on the effectiveness of home versus office-based phototherapy.