{"id":1038,"date":"2021-09-28T03:51:09","date_gmt":"2021-09-28T03:51:09","guid":{"rendered":"https:\/\/dermatology.upenn.edu\/training-new\/?p=1038"},"modified":"2023-08-02T16:12:42","modified_gmt":"2023-08-02T16:12:42","slug":"t32-trainer-david-allman-phd","status":"publish","type":"post","link":"https:\/\/dermatology.upenn.edu\/training\/2021\/09\/28\/t32-trainer-david-allman-phd\/","title":{"rendered":"David Allman, PhD"},"content":{"rendered":"<div id='av_section_1'  class='avia-section main_color avia-section-default avia-no-border-styling  avia-bg-style-scroll  avia-builder-el-0  avia-builder-el-no-sibling   container_wrap fullsize' style='background-color: #ffffff;  '  ><div class='container' ><main  role=\"main\" itemprop=\"mainContentOfPage\"  class='template-page content  av-content-full alpha units'><div class='post-entry post-entry-type-page post-entry-1038'><div class='entry-content-wrapper clearfix'>\n<div class=\"flex_column av_one_fourth  flex_column_div av-zero-column-padding first  avia-builder-el-1  el_before_av_two_third  avia-builder-el-first  \" style='border-radius:0px; '><p><div  class='avia-image-container  av-styling-    avia-builder-el-2  el_before_av_textblock  avia-builder-el-first  avia-align-left '  itemprop=\"image\" itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/ImageObject\"  ><div class='avia-image-container-inner'><div class='avia-image-overlay-wrap'><img decoding=\"async\" class='wp-image-1584 avia-img-lazy-loading-not-1584 avia_image' src=\"https:\/\/dermatology.upenn.edu\/training\/wp-content\/uploads\/sites\/13\/2021\/09\/allm1027-1.jpg\" alt='' title='allm1027' height=\"215\" width=\"160\"  itemprop=\"thumbnailUrl\"  \/><\/div><\/div><\/div><br \/>\n<section class=\"av_textblock_section \"  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/BlogPosting\" itemprop=\"blogPost\" ><div class='avia_textblock  '   itemprop=\"text\" ><h5>David Allman, PhD<\/h5>\n<p>Professor<\/p>\n<p>Associate Director, Abramson Cancer Center Flow Cytometry Core Facility<\/p>\n<p>Department of Pathology &amp; Laboratory Medicine<\/p>\n<p><span data-sheets-value=\"{\" data-sheets-userformat=\"{\">Perelman School of Medicine<\/span><\/p>\n<p><a href=\"mailto:dallman@pennmedicine.upenn.edu\"><span style=\"color: #0000ff\">Email<\/span><\/a><\/p>\n<p><a href=\"https:\/\/www.med.upenn.edu\/apps\/faculty\/index.php\/g275\/p16506\"><span style=\"color: #0000ff\">Faculty Webpage<\/span><\/a><\/p>\n<\/div><\/section><\/p><\/div><div class=\"flex_column av_two_third  flex_column_div av-zero-column-padding   avia-builder-el-4  el_after_av_one_fourth  avia-builder-el-last  \" style='border-radius:0px; '><p><section class=\"av_textblock_section \"  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/BlogPosting\" itemprop=\"blogPost\" ><div class='avia_textblock  '   itemprop=\"text\" ><p><b>About the Lab:<\/b><\/p>\n<p><span role=\"\" data-sheets-value=\"{\" data-sheets-userformat=\"{\">Interests of the Allman lab include: (a) Long-lived plasma cells in immunity and autoimmunity. (b) Metabolic regulation of B-lineage effector fates. The Allman lab discovered that rapamycin, an inhibitor of the metabolic regulatory mTORC1 kinase complex, selectively depletes germinal center and activated B cells when administered to previously immunized mice. They use genetic approaches to define the role of mTORC1 components in germinal center B cell differentiation and survival. Strategies to deplete activated B cells selectively may prove useful in many clinical settings including in autoimmune diseases such as pemphigus. <\/span><\/p>\n<\/div><\/section><br \/>\n<section class=\"av_textblock_section \"  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/BlogPosting\" itemprop=\"blogPost\" ><div class='avia_textblock  '   itemprop=\"text\" ><p><b>Training Information:<\/b><\/p>\n<p>Current and previous trainees have been highly productive and several of Dr. Allman\u2019s prior trainees are now postdoctoral researchers in basic or applied areas of immunology.<\/p>\n<\/div><\/section><\/p><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":764,"featured_media":3320,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_topic_count_hidden":0,"_bbp_reply_count_hidden":0,"_bbp_forum_subforum_count":0,"rop_custom_images_group":[],"rop_custom_messages_group":[],"rop_publish_now":"initial","rop_publish_now_accounts":[],"rop_publish_now_history":[],"rop_publish_now_status":"pending","footnotes":""},"categories":[65,21],"tags":[],"class_list":["post-1038","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-immunity","category-trainer"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.0 - 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