About the Lab:
The Kahn laboratory studies mechanism of blood and lymphatic vessel growth, with an emphasis on disease mechanism. The skin is an important site for the growth of both of these vessel types and the primary site for some vascular diseases, e.g. lymphedema, in humans. Dr. Kahn is using skin-specific genetic tools to both delete and activate angiogenic and lymphangiogenic signaling pathways in a spatially and temporally controlled manner in murine skin to better understand how these vessels are formed and maintained. His lab discovered that CCBE1 is required for lymphatic growth and function in the skin.