One of only six designated centers in the country, this program greatly enhances the ability of researchers to investigate skin biology and translate those findings to treat cutaneous diseases. PHILADELPHIA – Funding for the Penn Skin Biology and Diseases Resource-based Center (SBDRC), has been renewed for the next five years from the National Institute of …
Author: Penn SBDRC
Superhero scarless skin
Dr. Thomas Leung’s lab recently published an exciting paper in Science Immunology highlighting the nerve-skin-immune axis and its role in scarring and regeneration. Dr. Leung was supported by an SBDRC P&F Grant and utilized several of the Cores for the work. Below, we had the opportunity to learn about motivation for the work, current status, …
The Seeds of Cancer
Penn SBDRC-supported study identifies mutations and biomarkers associated with carcinoma in situ Mutations and biomarkers were examined in patient biopsies taken in the early stages of squamous cell carcinoma. Laser capture microdissection was coupled with exome-seq and RNA-seq of patient biopsies. The data provide new insights regarding the mutations that drive the formation of squamous …
Young Investigator Award – Lindsay Kalan
(Elizabeth Grice, Lindsay Kalan, and collaborator Sue Gardner from University of Iowa pictured above) Congratulations to Lindsay Kalan for receiving the 2017 Young Investigator Award by the Wound Healing Society. Lindsay Kalan qualified by scoring in the top 8 abstracts submitted to the Wound Healing Society, and her presentation of “Shotgun metagenomics and chronic non-healing …
SBDRC Pilot and Feasibility Grant Awards
Congratulations to our 2017 Pilot & Feasibility grant awardees! 2017 Full Grant Thomas Leung, Department of Dermatology SDF1 control of tissue regeneration and fibrosis in mice and humans Pantelis Rompolas, Department of Dermatology Notch regulation of stem cell fate in skin homeostasis and tumorigenesis Jonathan Katz, Department of Medicine The role of KLF4 in UV-mediated …
Penn Receives $4 Million NIH Grant for New Skin Biology and Diseases Resource-based Center
Funding Will Enable Expansion of Skin Research, More Rapid Translation into Patient Treatment PHILADELPHIA – The National Institute of Arthritis and Musculoskeletal and Skin Diseases of the National Institutes of Health has awarded Sarah E. Millar, PhD, the Albert M. Kligman Professor and Vice-Chair for Basic Research in the Department of Dermatology, and George Cotsarelis, …