Publications - Penn SBDRC

Publications resulting from Penn SBDRC support are listed below and updated as information is provided by our members.

**Penn SBDRC Members**

Please report publications and grants resulting from Penn SBDRC support HERE.
Please remember to acknowledge the SBDRC in your publications and abstracts. Acknowledgement in these publications is crucial for ongoing funding of our programs as it provides a tangible metric of our impact on skin research.
Penn SBDRC provides many forms of support that should be acknowledged including: pilot grants, resource cores, and enrichment programs.
You may use the following text to cite the SBDRC’s support in your publications: Support for this work was provided by the Penn Skin Biology and Diseases Resource-based Center, funded by NIH/NIAMS grant P30-AR069589 and the University of Pennsylvania Perelman School of Medicine.

2022

Aguirre-Portolés, C., Payne, R., Trautz, A., Foskett, J. K., Natale, C. A., Seykora, J. T., & Ridky, T. W. (2021). ZIP9 Is a Druggable Determinant of Sex Differences in Melanoma. Cancer Research, 81(23), 5991–6003.

Aira, L. E., & Debes, G. F. (2021). Skin-Homing Regulatory B Cells Required for Suppression of Cutaneous Inflammation. The Journal of Investigative Dermatology, 141(8), 1995-2005.e6.

Aldea, D., & Kamberov, Y. G. (2022). En1 sweat we trust: How the evolution of an Engrailed 1 enhancer made humans the sweatiest ape. Temperature, 0(0), 1–3.

Beattie, K., Jiang, H., Gautam, M., MacVittie, M. K., Miller, B., Ma, M., Liu, Q., & Luo, W. (2022). TRPC3 Antagonizes Pruritus in a Mouse Contact Dermatitis Model. The Journal of Investigative Dermatology, 142(4), 1136–1144.

Bhuju, J., Olesen, K. M., Muenyi, C. S., Patel, T. S., Read, R. W., Thompson, L., Skalli, O., Zheng, Q., Grice, E. A., Sutter, C. H., & Sutter, T. R. (2021a). Cutaneous Effects of In Utero and Lactational Exposure of C57BL/6J Mice to 2,3,7,8-Tetrachlorodibenzo-p-dioxin. Toxics, 9(8), 192.

Brennan-Crispi, D. M., Frankfurter, M., Murphy, C., Sheng, E., Xu, M., Morrisey, E. E., Millar, S. E., & Leung, T. H. (2022). FZD2 Regulates Murine Hair Follicle Function and Maintenance. The Journal of Investigative Dermatology, S0022-202X(22)00011-2.

Chen, K. L., Patel, J., Zeidi, M., Wysocka, M., Bashir, M. M., Patel, B., Maddukuri, S., White, B., & Werth, V. P. (2021). Myeloid Dendritic Cells Are Major Producers of IFN-β in Dermatomyositis and May Contribute to Hydroxychloroquine Refractoriness. The Journal of Investigative Dermatology, 141(8), 1906-1914.e2.

Choa, R., Tohyama, J., Wada, S., Meng, H., Hu, J., Okumura, M., May, R. M., Robertson, T. F., Pai, R.-A. L., Nace, A., Hopkins, C., Jacobsen, E. A., Haldar, M., FitzGerald, G. A., Behrens, E. M., Minn, A. J., Seale, P., Cotsarelis, G., Kim, B., … Kambayashi, T. (2021a). Thymic stromal lymphopoietin induces adipose loss through sebum hypersecretion. Science (New York, N.Y.), 373(6554), eabd2893.

Cui, L., Guo, J., Cranfill, S. L., Gautam, M., Bhattarai, J., Olson, W., Beattie, K., Challis, R. C., Wu, Q., Song, X., Raabe, T., Gradinaru, V., Ma, M., Liu, Q., & Luo, W. (2022). Glutamate in primary afferents is required for itch transmission. Neuron, 110(5), 809-823.e5.

Egolf, S., Zou, J., Anderson, A., Simpson, C. L., Aubert, Y., Prouty, S., Ge, K., Seykora, J. T., & Capell, B. C. (2021). MLL4 mediates differentiation and tumor suppression through ferroptosis. Science Advances, 7(50), eabj9141.

Farrelly, O., Suzuki-Horiuchi, Y., Brewster, M., Kuri, P., Huang, S., Rice, G., Bae, H., Xu, J., Dentchev, T., Lee, V., & Rompolas, P. (2021). Two-photon live imaging of single corneal stem cells reveals compartmentalized organization of the limbal niche. Cell Stem Cell.

Hatterschide, J., Castagnino, P., Kim, H. W., Sperry, S. M., Montone, K. T., Basu, D., & White, E. A. (2022). YAP1 activation by human papillomavirus E7 promotes basal cell identity in squamous epithelia. ELife, 11, e75466.

Huang, S., Kuri, P., Aubert, Y., Brewster, M., Li, N., Farrelly, O., Rice, G., Bae, H., Prouty, S., Dentchev, T., Luo, W., Capell, B. C., & Rompolas, P. (2021a). Lgr6 marks epidermal stem cells with a nerve-dependent role in wound re-epithelialization. Cell Stem Cell, 28(9), 1582-1596.e6.

Patel, Jay; Vazquez, Thomas; Werth, Victoria P. (2022). Multidimensional immune profiling of cutaneous lupus erythematosus in vivo stratified by patient responses to antimalarials. Mendeley Data, V1, doi: 10.17632/b7vr75sbdz.1

Ko, K. I., Merlet, J. J., DerGarabedian, B. P., Zhen, H., Suzuki-Horiuchi, Y., Hedberg, M. L., Hu, E., Nguyen, A. T., Prouty, S., Alawi, F., Walsh, M. C., Choi, Y., Millar, S. E., Cliff, A., Romero, J., Garvin, M. R., Seykora, J. T., Jacobson, D., & Graves, D. T. (2022). NF-κB perturbation reveals unique immunomodulatory functions in Prx1+ fibroblasts that promote development of atopic dermatitis. Science Translational Medicine, 14(630), eabj0324.

Li, M., Ferretti, M., Descamps, H., Lee, E., Dittmar, M., Lee, J. S., Whig, K., Kamalia, B., Dohnalova, L., Uhr, G., Zarkoob, H., Chen, Y.-C., Ramage, H., Ferrer, M., Lynch, K., Schultz, D. C., Thaiss, C. A., Diamond, M. S., & Cherry, S. (2021). Pharmacological activation of STING blocks SARS-CoV-2 infection. Science Immunology, 6(59), eabi9007.

Li, M., Lyu, X., Liao, J., Werth, V. P., & Liu, M.-L. (2021). Rho Kinase regulates neutrophil NET formation that is involved in UVB-induced skin inflammation [Preprint]. Pathology; BioRxiv.

Lundgren, P., Sharma, P. V., & Thaiss, C. A. (2021). A dietary source of antibiotic tolerance. Cell Metabolism, 33(8), 1516–1518.

Maddukuri, S., Patel, J., Diaz, D. A., Chen, K. L., Wysocka, M., Bax, C., Li, Y., Ravishankar, A., Grinnell, M., Zeidi, M., Reddy, N., Concha, J. S. S., Bashir, M. M., Okawa, J., White, B., & Werth, V. P. (2022). Cannabinoid type 2 receptor (CB2R) distribution in dermatomyositis skin and peripheral blood mononuclear cells (PBMCs) and in vivo effects of LenabasumTM. Arthritis Research & Therapy, 24(1), 12.

Maldonado López, A., & Capell, B. C. (2021). The METTL3-m6A Epitranscriptome: Dynamic Regulator of Epithelial Development, Differentiation, and Cancer. Genes, 12(7), 1019.

Patel, J., Ravishankar, A., Maddukuri, S., Vazquez, T., Grinnell, M., & Werth, V. P. (2021). Identification of Similarities Between Skin Lesions in Patients With Antisynthetase Syndrome and Skin Lesions in Patients With Dermatomyositis by Highly Multiplexed Imaging Mass Cytometry. Arthritis & Rheumatology (Hoboken, N.J.).

Peraramelli, S., Zhou, Q., Zhou, Q., Wanko, B., Zhao, L., Nishimura, T., Leung, T. H., Mizuno, S., Ito, M., Myles, T., Stulnig, T. M., Morser, J., & Leung, L. L. K. (2022). Thrombin cleavage of osteopontin initiates osteopontin’s tumor-promoting activity. Journal of Thrombosis and Haemostasis: JTH.

Sati, S., Jones, P., Kim, H. S., Zhou, L. A., Rapp-Reyes, E., & Leung, T. H. (2022). HiCuT: An efficient and low input method to identify protein-directed chromatin interactions. PLoS Genetics, 18(3), e1010121.

Taylor, M. T., Noe, M. H., Horton, D. B., & Barbieri, J. S. (2021). Trends in opioid prescribing at outpatient visits for psoriasis and psoriatic arthritis. The British Journal of Dermatology, 185(1), 200–201.

Tovanabutra, N., Bax, C. E., Feng, R., Kushner, C. J., & Payne, A. S. (2022). Temporal Outcomes after Rituximab Therapy for Pemphigus Vulgaris. The Journal of Investigative Dermatology, 142(4), 1058-1064.e7.

Uberoi, A., Bartow-McKenney, C., Zheng, Q., Flowers, L., Campbell, A., Knight, S. A. B., Chan, N., Wei, M., Lovins, V., Bugayev, J., Horwinski, J., Bradley, C., Meyer, J., Crumrine, D., Sutter, C. H., Elias, P., Mauldin, E., Sutter, T. R., & Grice, E. A. (2021a). Commensal microbiota regulates skin barrier function and repair via signaling through the aryl hydrocarbon receptor. Cell Host & Microbe, 29(8), 1235-1248.e8.

Wehner, M. R., Niu, J., Wheless, L., Baker, L. X., Cohen, O. G., Margolis, D. J., Giordano, S. H., & Shin, T. M. (2021). Risks of Multiple Skin Cancers in Organ Transplant Recipients: A Cohort Study in 2 Administrative Data Sets. JAMA Dermatology, 157(12), 1447–1455.

Zeidi, M., Chen, K. L., Patel, J., Desai, K., Kim, H. J., Chakka, S., Lim, R., & Werth, V. P. (2022). Increased CD69+CCR7+ circulating activated T cells and STAT3 expression in cutaneous lupus erythematosus patients recalcitrant to antimalarials. Lupus, 31(4), 472–481.

Zhu, G., Herlyn, M., & Yang, X. (2021). TRIM15 and CYLD regulate ERK activation via lysine-63-linked polyubiquitination. Nature Cell Biology, 23(9), 978–991.

Zhu, X., Leboeuf, M., Liu, F., Grachtchouk, M., Seykora, J. T., Morrisey, E. E., Dlugosz, A. A., & Millar, S. E. (2021a). HDAC1/2 Control Proliferation and Survival in Adult Epidermis and Pre‒Basal Cell Carcinoma through p16 and p53. The Journal of Investigative Dermatology, S0022-202X(21)01438-X.

2021

Aldea D, Atsuta Y, Kokalari B, Schaffner SF, Prasasya RD, Aharoni A, Dingwall HL, Warder B, Kamberov YG. Repeated mutation of a developmental enhancer contributed to human thermoregulatory evolution. Proc Natl Acad Sci U S A. 2021 Apr 20;118(16):e2021722118. doi: 10.1073/pnas.2021722118. PMID: 33850016. PMCID: PMC8072367.

Farrelly O, Suzuki-Horiuchi Y, Brewster M, Kuri P, Huang S, Rice G, Bae H, Xu J, Dentchev T, Lee V, Rompolas P. Two-photon live imaging of single corneal stem cells reveals compartmentalized organization of the limbal niche. Cell Stem Cell. 2021 May 3:S1934-5909. PMID: 33984283.

Moore AS, Coscia SM, Simpson CL, Ortega FE, Wait EC, Heddleston JM, Nirschl JJ, Obara CJ, Guedes-Dias P, Boecker CA, Chew TL, Theriot JA, Lippincott-Schwartz J, Holzbaur ELF. Actin cables and comet tails organize mitochondrial networks in mitosis. Nature. 2021 Mar;591(7851):659-664. doi: 10.1038/s41586-021-03309-5. Epub 2021 Mar 3. PMID: 33658713.

Patel J, Maddukuri S, Li Y, Bax C, Werth VP. Highly multiplexed mass cytometry identifies the immunophenotype in the skin of dermatomyositis. J Invest Dermatol. 2021 Mar 22 online ahead of print.

Roche FC, Fischer AS, Gaddis KJ, Dentchev T, Taylor SC, Cotsarelis G, Seykora JT. Fibrotic trochanters: A potential mechanism for stem cell depletion in scarring alopecias. J Cutan Pathol. 2021 Mar;48(3):458-460. PMID: 32844450.

Simpson CL, Tokito MK, Uppala R, Sarkar MK, Gudjonsson JE, Holzbaur ELF. NIX initiates mitochondrial fragmentation via DRP1 to drive epidermal differentiation. Cell Rep. 2021 Feb 2;34(5):108689. doi: 10.1016/j.celrep.2021.108689. PMID: 33535046. PMCID: PMC7888979

Syed MN, Shah M, Shin DB, Wan MT, Winthrop KL, Gelfand JM. Effect of anti-tumor necrosis factor therapy on the risk of respiratory tract infections and related symptoms in patients with psoriasis-A meta-estimate of pivotal phase 3 trials relevant to decision making during the COVID-19 pandemic. J Am Acad Dermatol. 2021 Jan;84(1):161-163. PMID: 32860913. PMCID: PMC7448776.

Zheng Q, Capell BC, Parekh V, O’Day C, Atillasoy C, Bashir HM, Shim E, Yeh C, Prouty SM, Pear W, Grice EA, Seykora JT. Whole exome and transcriptome analysis of UV-exposed epidermis and carcinoma in situ reveals early drivers of carcinogenesis. J Invest Dermatol. 2021 Feb 2;141(2):295-308.e13; PMID: 32649944. NIHMSID: 1613087.

2020

Alvarez Y, Glotfelty LG, Blank N, Dohnalova L, Thaiss CA. The Microbiome as a Circadian Coordinator of Metabolism. Endocrinology. 2020 Jun 1;161(6):bqaa059. PMID: 32291454. PMCID: PMC7899566.

Barbieri JS, Shin DB, Syed MN, Takeshita J, Gelfand JM. Evaluation of the Frequency of “Not Relevant” Responses on the Dermatology Life Quality Index by Sociodemographic Characteristics of Patients With Psoriasis. JAMA Dermatol. 2020 Feb 26; PMCID: PMC7142381.

Barbieri JS, Shin DB, Wang S, Margolis DJ, Takeshita J. The clinical utility of laboratory monitoring during isotretinoin therapy for acne and changes to monitoring practices over time. J Am Acad Dermatol. 2020 Jan;82(1):72-79. PMID: 31228528; PMCID: PMC6911828.

Berna R, Mitra N, Hoffstad O, Wan J, Margolis DJ. Identifying Phenotypes of Atopic Dermatitis in a Longitudinal United States Cohort Using Unbiased Statistical Clustering. J Invest Dermatol. 2020 Feb 1;140(2):477–479. PMCID: PMC6983356.

Cohen OG, Margolis DJ, Wehner MR. The validity of diagnostic and treatment codes for actinic keratosis in electronic health records. Br J Dermatol. 2020 Jun;182(6):1487–1488. PMCID: PMC7266709.

Flamm A, Moshiri AS, Roche F, Onyekaba G, Nguyen J, James AJ, Taylor S, Seykora JT. Characterization of the inflammatory features of central centrifugal cicatricial alopecia. J Cutan Pathol. 2020 Feb 18; PMID: 32068905. NIHMSID: 1613096.

Guo CJ, Mack MR, Oetjen LK, Trier AM, Council ML, Pavel AB, Guttman-Yassky E, Kim BS, Liu Q. Kallikrein 7 Promotes Atopic Dermatitis-Associated Itch Independently of Skin Inflammation. J Invest Dermatol. 2020 Jun;140(6):1244-1252.e4. PMCID: PMC7247952.

Lee J, Lundgren DK, Mao X, Manfredo-Vieira S, Nunez-Cruz S, Williams EF, Assenmacher CA, Radaelli E, Oh S, Wang B, Ellebrecht CT, Fraietta JA, Milone MC, Payne AS. Antigen-specific B cell depletion for precision therapy of mucosal pemphigus vulgaris. J Clin Invest. 2020 Dec 1;130(12):6317-6324. doi: 10.1172/JCI138416. PMID: 32817591. PMCID: PMC7685721

Lee V, Gober MD, Bashir H, O’Day C, Blair IA, Mesaros C, Weng L, Huang A, Chen A, Tang R, Anagnos V, Li J, Roling S, Sagaityte E, Wang A, Lin C, Yeh C, Atillasoy C, Marshall C, Dentchev T, Ridky T, Seykora JT. Voriconazole enhances UV-induced DNA damage by inhibiting catalase and promoting oxidative stress. Exp Dermatol. 2020 Jan;29(1):29-38. PMID: 31519066. PMCID: PMC7401379.

Li Y, Li M, Weigel B, Mall M, Werth VP, Liu M-L. Nuclear envelope rupture and NET formation is driven by PKCα-mediated lamin B disassembly. EMBO Rep. 2020 Jun 15;e48779. PMID: 32537912. NIHMSID: 1615083.

Liu W, Kim GB, Krump NA, Zhou Y, Riley JL, You J. Selective reactivation of STING signaling to target Merkel cell carcinoma. Proc Natl Acad Sci USA. 2020 Jun 16;117(24):13730–13739. PMCID: PMC7306767.

Liu W, Krump NA, Herlyn M, You J. Combining DNA Damage Induction with BCL-2 Inhibition to Enhance Merkel Cell Carcinoma Cytotoxicity. Biology (Basel). 2020 Feb 19;9(2). PMCID: PMC7168258.

Lundgren P and Thaiss CA. The microbiome-adipose tissue axis in systemic metabolism. Am J Physiol Gastrointest Liver Physiol. 2020 Apr 1;318(4):G717-G724. PMID: 32068441. PMCID: PMC7191461.

Micheletti RG, Chansky PB, Haun PL, Seykora JT, Dekerlegand J, Sultan LR, Schultz SM, Sehgal CM, Sobanko JF. Ablative fractional laser resurfacing for treatment of sclerosis and contractures in chronic graft-versus-host disease: A pilot study. J Am Acad Dermatol. 2020 Apr;82(4):984–986. PMID: 31374309. NIHMSID: 1613119.

Natale CA, Li J, Pitarresi JR, Norgard RJ, Dentchev T, Capell BC, Seykora JT, Stanger BZ, Ridky TW. Pharmacologic Activation of the G Protein-Coupled Estrogen Receptor Inhibits Pancreatic Ductal Adenocarcinoma. Cell Mol Gastroenterol Hepatol. 2020;10(4)868-880.e1. PMID: 32376419. PMCID: PMC7578406.

Nguyen CV, Gaddis KJ, Stephens MR, Seykora JT, Chu EY. An Intrapatient Concordance Study of Mismatch Repair Protein Immunohistochemical Staining Patterns in Patients With Muir-Torre Syndrome. JAMA Dermatol. 2020 Apr 8; PMCID: PMC7142808.

Noe MH, Gelfand JM, Bryer JS, Price SN, Judson MA, Rosenbach M. Responsiveness to Change and Establishment of the Minimal Clinically Important Difference for the Cutaneous Sarcoidosis Activity and Morphology Instrument. JAMA Dermatol. 2020 Jan 1;156(1):98-99. PMID: 31721981; PMCID: PMC6865242.

Noe MH, Shin DB, Wehner MR, Margolis DJ, Gelfand JM. Opioid Prescribing in Adults with and without Psoriasis. J Am Acad Dermatol. 2020 Apr 1; PMID: 32246971. NIHMSID: 1581367.

Sharma PV and Thaiss CA. Host-Microbiome Interactions in the Era of Single-Cell Biology. Front Cell Infect Microbiol. 2020 Oct 14;10:569070. PMID: 33163417. PMCID: PMC7591464.

Shields BE, Gelfand JM, Allen-Taylor L, Rosenbach M. Prevalence of Dermatitis Herpetiformis Within the iCureCeliac Patient-Powered Research Network-Patient Characteristics and Dietary Counseling. JAMA Dermatol. 2020 Dec 1;156(12):1374-1376. PMID:33026427. PMCID: PMC7542518.

Syed MN, Shin DB, Wan MT, Winthrop KL, Gelfand JM. The risk of respiratory tract infections in patients with psoriasis treated with interleukin 23 pathway-inhibiting biologics: A meta-estimate of pivotal trials relevant to decision making during the COVID-19 pandemic. J Am Acad Dermatol. 2020 Nov;83(5):1523-1526. PMID: 32622891. PMCID: PMC7331500.

Szigety KM, Liu F, Yuan CY, Moran DJ, Horrell J, Gochnauer HR, Cohen RN, Katz JP, Kaestner KH, Seykora JT, Tobias JW, Lazar MA, Xu M, Millar SE. HDAC3 ensures stepwise epidermal stratification via NCoR/SMRT-reliant mechanisms independent of its histone deacetylase activity. Genes Dev. 2020 Jul 1;34(13–14):973–988. PMCID: PMC7328513.

Wan J, Shin DB, Gelfand JM. Association between atopic dermatitis and learning disability in children. J Allergy Clin Immunol Pract. 2020 Sep;8(8):2808-2810. PMID: 32348912; PMCID: PMC7483744.

Wan J, Takeshita J, Shin DB, Gelfand JM. Mental health impairment among children with atopic dermatitis: A United States population-based cross-sectional study of the 2013-2017 National Health Interview Survey. J Am Acad Dermatol. 2020 Jun;82(6):1368-1375. PMID: 31626880; PMCID: PMC7156313.

Wan MT, Pearl RL, Chiesa Fuxench ZC, Takeshita J, Gelfand JM. Anticipated and Perceived Stigma Among Patients With Psoriasis. J Psoriasis Psoriatic Arthritis. 2020 Jul;5(3):93-99. PMID: 33733037; PMCID: PMC7963348.

Wang LL, Moshiri AS, Novoa R, Simpson CL, Takeshita J, Payne AS, Chu EY. Comparison of C3d immunohistochemical staining to enzyme-linked immunosorbent assay and immunofluorescence for diagnosis of bullous pemphigoid. J Am Acad Dermatol. 2020 Feb 14; PMID: 32068042. NIHMSID: 1615716.

Wei JJ, Kim HS, Spencer, CA, Brennan-Crispi D, Zheng Y, Johnson NM, Rosenbach M, Miller C, Leung DH, Cotsarelis G, Leung TH. Activation of TRPA1 nociceptor promotes systemic adult mammalian skin regeneration. Sci Immun. 2020 Aug 28;5(50) PMID: 32859683.

Yu K, Syed MN, Bernardis E, Gelfand JM. Machine Learning Applications in the Evaluation and Management of Psoriasis: A Systematic Review. J Psoriasis Psoriatic Arthritis. 2020 Oct;5(4):147-159. PMID: 33733038; PMCID: PMC7963214.

2019

Amorim CF, Novais FO, Nguyen BT, Misic AM, Carvalho LP, Carvalho EM, Beiting DP, Scott P. Variable gene expression and parasite load predict treatment outcome in cutaneous leishmaniasis. Sci Transl Med. 2019 20;11(519). PMCID: PMC7068779.

Aubert Y, Egolf S, Capell BC. The Unexpected Noncatalytic Roles of Histone Modifiers in Development and Disease. Trends Genet. 2019;35(9):645–657. PMCID: PMC6697606.

Barbieri JS, Choi JK, James WD, Margolis DJ. Real-world drug usage survival of spironolactone versus oral antibiotics for the management of female patients with acne. J Am Acad Dermatol. 2019 Sep 1;81(3):848–851. PMCID: PMC6698210.

Barbieri JS, Etzkorn JR, Margolis DJ. Use of Antibiotics for Dermatologic Procedures From 2008 to 2016. JAMA Dermatol. 2019 Apr 1;155(4):465–470. PMCID: PMC6459091.

Barbieri JS, Gelfand JM. Evaluation of the Dermatology Life Quality Index scoring modification, the DLQI-R score, in two independent populations. Br J Dermatol. 2019 Apr 1;180(4):939–940. PMCID: PMC6443498.

Barbieri JS, Gelfand JM. Influence of “Not Relevant” Responses on the Dermatology Life Quality Index (DLQI) for Patients With Psoriasis in the United States. JAMA Dermatol. 2019 Jun 1;155(6):743–745. PMCID: PMC6533805.

Barbieri JS, Gelfand JM. Responsiveness of the EuroQol 5-Dimension 3-Level instrument, Dermatology Life Quality Index (DLQI) and DLQI-Relevant for patients with psoriasis in the U.S.A. Br J Dermatol. 2019 Nov 1;181(5):1088–1090. PMID: 31102266. NIHMSID: 1615050.

Debes GF, McGettigan SE. Skin-Associated B Cells in Health and Inflammation. J Immunol. 2019 15;202(6):1659–1666. PMCID: PMC6402607.

Descamps HC, Herrmann B, Wiredu D, Thaiss CA. The path toward using microbial metabolites as therapies. EBioMedicine. 2019 Jun 1;44:747–754. PMCID: PMC6606739.

Egolf S, Aubert Y, Doepner M, Anderson A, Maldonado-Lopez A, Pacella G, Lee J, Ko EK, Zou J, Lan Y, Simpson CL, Ridky T, Capell BC. LSD1 Inhibition Promotes Epithelial Differentiation through Derepression of Fate-Determining Transcription Factors. Cell Rep. 2019 Aug 20;28(8):1981-1992.e7. PMCID: PMC6719800.

Farrelly O, Kuri P, Rompolas P. In Vivo Genetic Alteration and Lineage Tracing of Single Stem Cells by Live Imaging. Methods Mol Biol. 2019;1879:1–14. PMID: 30242568. NIHMSID: 1612800.

Grogan MD, Bartow-McKenney C, Flowers L, Knight SAB, Uberoi A, Grice EA. Research Techniques Made Simple: Profiling the Skin Microbiota. J Invest Dermatol. 2019 Apr 1;139(4):747-752.e1. PMID: 30904077. NIHMSID: 1612706.

Jaitin DA, Adlung L, Thaiss CA, Weiner A, Li B, Descamps H, Lundgren P, Bleriot C, Liu Z, Deczkowska A, Keren-Shaul H, David E, Zmora N, Eldar SM, Lubezky N, Shibolet O, Hill DA, Lazar MA, Colonna M, Ginhoux F, Shapiro H, Elinav E, Amit I. Lipid-Associated Macrophages Control Metabolic Homeostasis in a Trem2-Dependent Manner. Cell. 2019 Jul 25;178(3):686-698.e14. PMID: 31257031; PMCID: PMC7068689.

Kalan LR, Meisel JS, Loesche MA, Horwinski J, Soaita I, Chen X, Uberoi A, Gardner SE, Grice EA. Strain- and Species-Level Variation in the Microbiome of Diabetic Wounds Is Associated with Clinical Outcomes and Therapeutic Efficacy. Cell Host Microbe. 2019 May 8;25(5):641-655.e5. PMCID: PMC6526540.

Liu W, Krump NA, Buck CB, You J. Merkel Cell Polyomavirus Infection and Detection. J Vis Exp. 2019 07;(144). PMCID: PMC6656558.

Ma SA, O’Day CP, Dentchev T, Takeshita J, Ridky TW, Seykora JT, Chu EY. Expression of p15 in a spectrum of spitzoid melanocytic neoplasms. J Cutan Pathol. 2019 May 1;46(5):310–316. PMCID: PMC6506222.

Meixiong J, Anderson M, Limjunyawong N, Sabbagh MF, Hu E, Mack MR, Oetjen LK, Wang F, Kim BS, Dong X. Activation of Mast-Cell-Expressed Mas-Related G-Protein-Coupled Receptors Drives Non-histaminergic Itch. Immunity. 2019 May 21;50(5):1163-1171.e5. PMCID: PMC6531358.

Monteleon CL, Lee IY, Ridky TW. Exophilin-5 Supports Lysosome-Mediated Trafficking Required for Epidermal Differentiation. J Invest Dermatol. 2019 Oct 1;139(10):2219-2222.e6. PMCID: PMC6814185.

Noe MH, Wan MT, Shin DB, Armstrong AW, Duffin KC, Fuxench ZCC, Kalb RE, Menter A, Simpson EL, Takeshita J, Tyring SK, Voorhees ASV, Mehta NN, Gelfand JM. Patient-reported outcomes of adalimumab, phototherapy, and placebo in the Vascular Inflammation in Psoriasis Trial: A randomized controlled study. J Am Acad Dermatol. 2019 Oct 1;81(4):923–930. PMCID: PMC6746579.

Parekh V, Sobanko J, Miller CJ, Karakousis G, Xu W, Letrero R, Elenitsas R, Xu X, Elder DE, Amaravadi R, Schuchter LM, Nathanson KL, Wilson MA, Chu EY. NRAS Q61R and BRAF G466A mutations in atypical melanocytic lesions newly arising in advanced melanoma patients treated with vemurafenib. J Cutan Pathol. 2019 Mar 1;46(3):190–194. PMCID: PMC6367041.

Pearl RL, Wan MT, Takeshita J, Gelfand JM. Stigmatizing attitudes toward persons with psoriasis among laypersons and medical students. J Am Acad Dermatol. 2019 Jun 1;80(6):1556–1563. PMCID: PMC6688164.

Spencer CA, Leung TH. Research Techniques Made Simple: Parabiosis to Elucidate Humoral Factors in Skin Biology. J Invest Dermatol. 2019 Jun 1;139(6):1208-1213.e1. PMCID: PMC6540816.

Uhr GT, Dohnalova L, Thaiss CA. The Dimension of Time in Host-Microbiome Interactions. mSystems. 2019 Feb 19;4(1):10.1128/mSystems.00216-Feb. PMCID: PMC6381226.

Wan MT, Torigian DA, Alavi A, Alvarez J, Fuxench ZCC, Noe MH, Papadopoulos M, Shin DB, Takeshita J, Werner TJ, Mehta NN, Gelfand JM. Prevalence of clinically significant incidental findings by whole-body fludeoxyglucose F 18 positron emission tomography/computed tomography scanning in moderate-to-severe psoriasis patients participating in clinical trials. J Am Acad Dermatol. 2019 Jun 1;80(6):1630–1639. PMCID: PMC6536299.

Wilson RP, McGettigan SE, Dang VD, Kumar A, Cancro MP, Nikbakht N, Stohl W, Debes GF. IgM Plasma Cells Reside in Healthy Skin and Accumulate with Chronic Inflammation. J Invest Dermatol. 2019 Dec 1;139(12):2477–2487. PMCID: PMC6874734.

Yang X, Daifallah AEM, Shankar S, Beer J, Marshall C, Dentchev T, Seykora F, D’Armas S, Hahn J, Lee V, Sabry HH, Farag AM, Seykora JT. Topical kinase inhibitors induce regression of cutaneous squamous cell carcinoma. Exp Dermatol. 2019 May 1;28(5):609–613. PMCID: PMC6520110.

Zeidi M, Kim HJ, Werth VP. Increased Myeloid Dendritic Cells and TNF-alpha Expression Predicts Poor Response to Hydroxychloroquine in Cutaneous Lupus Erythematosus. J Invest Dermatol. 2019 Feb 1;139(2):324–332. PMID: 30227141. NIHMSID: 1615122.

2018

Ellebrecht CT, Mukherjee EM, Zheng Q, Choi EJ, Reddy SG, Mao X, Payne AS. Autoreactive IgG and IgA B Cells Evolve through Distinct Subclass Switch Pathways in the Autoimmune Disease Pemphigus Vulgaris. Cell Rep. 2018 Aug 28;24(9):2370-2380. PMCID: PMC6156788.

Ghosh K, O’Neil K, Capell BC. Histone modifiers: Dynamic regulators of the cutaneous transcriptome. J Dermatol Sci. 2018 Mar;89(3):226–232. PMCID: PMC5828874.

Kim HJ, Zeidi M, Bonciani D, Pena SM, Tiao J, Sahu S, Werth VP. Itch in dermatomyositis: the role of increased skin interleukin-31. Br J Dermatol. 2018 Sep 1;179(3):669–678. PMCID: PMC6119520.

Lee S, Cieply B, Yang Y, Peart N, Glaser C, Chan P, Carstens RP. Esrp1-Regulated Splicing of Arhgef11 Isoforms Is Required for Epithelial Tight Junction Integrity. Cell Rep. 2018 Nov 27;25(9):2417-2430.e5. PMCID: PMC6371790.

Lin-Shiao E, Lan Y, Coradin M, Anderson A, Donahue G, Simpson CL, Sen P, Saffie R, Busino L, Garcia BA, Berger SL, Capell BC. KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis. Genes Dev. 2018 Jan 15;32(2):181–193. PMCID: PMC5830930.

Liu W, Krump NA, MacDonald M, You J. Merkel Cell Polyomavirus Infection of Animal Dermal Fibroblasts. J Virol. 2018 Jan 30;92(4):10.1128/JVI.01610-17. Print 2018 Feb 15. PMCID: PMC5790942.

Meisel JS, Sfyroera G, Bartow-McKenney C, Gimblet C, Bugayev J, Horwinski J, Kim B, Brestoff JR, Tyldsley AS, Zheng Q, Hodkinson BP, Artis D, Grice EA. Commensal microbiota modulate gene expression in the skin. Microbiome. 2018 Jan 30;6(1):20–9. PMCID: PMC5789709.

Monteleon CL, Agnihotri T, Dahal A, Liu M, Rebecca VW, Beatty GL, Amaravadi RK, Ridky TW. Lysosomes Support the Degradation, Signaling, and Mitochondrial Metabolism Necessary for Human Epidermal Differentiation. J Invest Dermatol. 2018 Sep 1;138(9):1945–1954. PMCID: PMC6521870.

Natale CA, Li J, Zhang J, Dahal A, Dentchev T, Stanger BZ, Ridky TW. Activation of G protein-coupled estrogen receptor signaling inhibits melanoma and improves response to immune checkpoint blockade. Elife. 2018 Jan 16;7:10.7554/eLife.31770. PMCID: PMC5770157.

Nishiguchi MA, Spencer CA, Leung DH, Leung TH. Aging Suppresses Skin-Derived Circulating SDF1 to Promote Full-Thickness Tissue Regeneration. Cell Rep. 2018 Dec 26;25(13):3898. PMCID: PMC6375300.

Noe MH, Gelfand JM. Research Techniques Made Simple: Pharmacoepidemiology Research Methods in Dermatology. J Invest Dermatol. 2018 Feb 1;138(2):e13–e18. PMCID: PMC5798480.

Shao K, Parker JC, Taylor L, Mitra N, Sobanko JF. Reliability of the Patient and Observer Scar Assessment Scale When Used With Postsurgical Scar Photographs. Dermatol Surg. 2018 Dec;44(12). PMID: 29381545. NIHMSID: 1616541.

Shao K, Zhang J, Pearl RL, Taylor L, Sobanko JF. Improving Quality of Life Measurement in Skin Cancer Patients: Clinical Correlate for the Skin Cancer Index. Dermatol Surg. 2018 Aug;44(8):1139–1140. PMID: 30045144. NIHMSID: 1616134.

Shaw L, Mansfield C, Colquitt L, Lin C, Ferreira J, Emmetsberger J, Reed DR. Personalized expression of bitter “taste” receptors in human skin. PLoS One. 2018 Oct 17;13(10):e0205322. PMCID: PMC6192714.

Song Y, Boncompagni AC, Kim SS, Gochnauer HR, Zhang Y, Loots GG, Wu D, Li Y, Xu M, Millar SE. Regional Control of Hairless versus Hair-Bearing Skin by Dkk2. Cell Rep. 2018 Dec 11;25(11):2981-2991.e3. PMCID: PMC6345517.

Stewart CL, Cornejo CM, Wanat KA, Sander I, Samimi S, Prouty S, Seykora J, Zhang P, Rosenbach M, Kim EJ, Micheletti RG. The immune reconstitution of the skin following sex-mismatched allogeneic haematopoietic stem cell transplant: a prospective case series utilizing fluorescence in situ hybridization and immunohistochemistry. Br J Dermatol. 2018 Jan 1;178(1):e55–e56. PMCID: PMC6036615.

Wan MT, Shin DB, Hubbard RA, Noe MH, Mehta NN, Gelfand JM. Psoriasis and the risk of diabetes: A prospective population-based cohort study. J Am Acad Dermatol. 2018;78(2):315-322.e1. PMCID: PMC5768452.

Wing A, Fajardo CA, Posey AD, Shaw C, Da T, Young RM, Alemany R, June CH, Guedan S. Improving CART-Cell Therapy of Solid Tumors with Oncolytic Virus-Driven Production of a Bispecific T-cell Engager. Cancer Immunol Res. 2018 May 1;6(5):605–616. PMCID: PMC6688490.

Xin T, Gonzalez D, Rompolas P, Greco V. Flexible fate determination ensures robust differentiation in the hair follicle. Nat Cell Biol. 2018;20(12):1361–1369. PMCID: PMC6314017.

Zheng Q, Bartow-McKenney C, Meisel JS, Grice EA. HmmUFOtu: An HMM and phylogenetic placement based ultra-fast taxonomic assignment and OTU picking tool for microbiome amplicon sequencing studies. Genome Biol. 2018 Jun 27;19(1):82–0. PMCID: PMC6020470.

2017

Castelo-Soccio L, McMahon P. Pediatric Dermatology. J Clin Aesthet Dermatol. 2017 Mar;10(3):S8–S15. PMCID: PMC5367868.

Chen J, Zheng Q, Hammers CM, Ellebrecht CT, Mukherjee EM, Tang HY, Lin C, Yuan H, Pan M, Langenhan J, Komorowski L, Siegel DL, Payne AS, Stanley JR. Proteomic Analysis of Pemphigus Autoantibodies Indicates a Larger, More Diverse, and More Dynamic Repertoire than Determined by B Cell Genetics. Cell Rep. 2017 Jan 3;18(1):237–247. PMCID: PMC5221611.

Christensen T, Yang JS, Castelo-Soccio L. Bullying and Quality of Life in Pediatric Alopecia Areata. Skin Appendage Disord. 2017 Aug;3(3):115–118. PMCID: PMC5582476.

Dou Z, Ghosh K, Vizioli MG, Zhu J, Sen P, Wangensteen KJ, Simithy J, Lan Y, Lin Y, Zhou Z, Capell BC, Xu C, Xu M, Kieckhaefer JE, Jiang T, Shoshkes-Carmel M, Tanim KMAA, Barber GN, Seykora JT, Millar SE, Kaestner KH, Garcia BA, Adams PD, Berger SL. Cytoplasmic chromatin triggers inflammation in senescence and cancer. Nature. 2017 Oct 19;550(7676):402–406. PMCID: PMC5850938.

Fischer AH, Shin DB, Margolis DJ, Takeshita J. Racial and ethnic differences in health care utilization for childhood eczema: An analysis of the 2001-2013 Medical Expenditure Panel Surveys. J Am Acad Dermatol. 2017 Dec;77(6):1060–1067. PMCID: PMC5916760.

Fuxench ZCC, Troxel AB, Gelfand JM. Validity of diagnostic codes for identifying cutaneous squamous cell carcinoma in The Health Improvement Network. Br J Dermatol. 2017 May 1;176(5):1363–1365. PMCID: PMC5303691.

Gaillard D, Bowles SG, Salcedo E, Xu M, Millar SE, Barlow LA. Beta-Catenin is Required for Taste Bud Cell Renewal and Behavioral Taste Perception in Adult Mice. PLoS Genet. 2017 Aug 28;13(8):e1006990. PMCID: PMC5591015.

Grewal SK, Wan J, Denburg MR, Shin DB, Takeshita J, Gelfand JM. The risk of IgA nephropathy and glomerular disease in patients with psoriasis: a population-based cohort study. Br J Dermatol. 2017;176(5):1366–1369. PMCID: PMC5303688.

Hannigan GD, Zheng Q, Meisel JS, Minot SS, Bushman FD, Grice EA. Evolutionary and functional implications of hypervariable loci within the skin virome. PeerJ. 2017;5:e2959. PMCID: PMC5299996.

Huang S, Rompolas P. Two-photon microscopy for intracutaneous imaging of stem cell activity in mice. Exp Dermatol. 2017 May 1;26(5):379–383. PMID: 27676122. NIHMSID: 1612819.

Kim HJ, Langenhan JL, Robinson ES, Privette E, Achtman JC, Mitrani RA, Zeidi M, Sharma MR, Feng R, Nevas JL, Calianno C, Okawa J, Taylor L, Pappas-Taffer L, Werth VP. Effect of long-term treatment with tumour necrosis factor-alpha inhibitors on single-dose ultraviolet-induced changes in human skin. Br J Dermatol. 2017 Dec 1;177(6):1762–1764. PMID: 28815549. NIHMSID: 1615118.

Loesche M, Gardner SE, Kalan L, Horwinski J, Zheng Q, Hodkinson BP, Tyldsley AS, Franciscus CL, Hillis SL, Mehta S, Margolis DJ, Grice EA. Temporal Stability in Chronic Wound Microbiota Is Associated With Poor Healing. J Invest Dermatol. 2017;137(1):237–244. PMCID: PMC5279919.

Ma SA, Imadojemu S, Beer K, Seykora JT. Inflammatory features of frontal fibrosing alopecia. J Cutan Pathol. 2017 Aug 1;44(8):672–676. PMCID: PMC6037423.

Mao X, Cho MJT, Ellebrecht CT, Mukherjee EM, Payne AS. Stat3 regulates desmoglein 3 transcription in epithelial keratinocytes. JCI Insight. 2017 May 4;2(9):10.1172/jci.insight.92253. PMCID: PMC5414550.

Noe MH, Grewal SK, Shin DB, Ogdie A, Takeshita J, Gelfand JM. Increased prevalence of HCV and hepatic decompensation in adults with psoriasis: a population-based study in the United Kingdom. J Eur Acad Dermatol Venereol. 2017 Oct 1;31(10):1674–1680. PMCID: PMC5653402.

Noe MH, Rodriguez O, Taylor L, Sultan L, Sehgal C, Schultz S, Gelfand JM, Judson MA, Rosenbach M. High frequency ultrasound: a novel instrument to quantify granuloma burden in cutaneous sarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis. 2017;34(2):136–141. PMCID: PMC5889145.

O’Connor DM, Jew OS, Perman MJ, Castelo-Soccio LA, Winston FK, McMahon PJ. Diagnostic Accuracy of Pediatric Teledermatology Using Parent-Submitted Photographs: A Randomized Clinical Trial. JAMA Dermatol. 2017 01;153(12):1243–1248. PMCID: PMC5817452.

Ogdie A, Harter L, Shin D, Baker J, Takeshita J, Choi HK, Love TJ, Gelfand JM. The risk of fracture among patients with psoriatic arthritis and psoriasis: a population-based study. Ann Rheum Dis. 2017 May;76(5):882–885. PMCID: PMC5384863.

Patel D, Castelo-Soccio LA, Rubin AI, Streicher JL. Laboratory Monitoring During Systemic Terbinafine Therapy for Pediatric Onychomycosis. JAMA Dermatol. 2017 01;153(12):1326–1327. PMCID: PMC5817446.

Patel D, Li P, Bauer AJ, Castelo-Soccio L. Screening Guidelines for Thyroid Function in Children With Alopecia Areata. JAMA Dermatol. 2017 01;153(12):1307–1310. PMCID: PMC5817442.

Patel DP, Swink SM, Castelo-Soccio L. A Review of the Use of Biotin for Hair Loss. Skin Appendage Disord. 2017 Aug;3(3):166–169. PMCID: PMC5582478.

Plikus MV, Guerrero-Juarez CF, Ito M, Li YR, Dedhia PH, Zheng Y, Shao M, Gay DL, Ramos R, Hsi TC, Oh JW, Wang X, Ramirez A, Konopelski SE, Elzein A, Wang A, Supapannachart RJ, Lee HL, Lim CH, Nace A, Guo A, Treffeisen E, Andl T, Ramirez RN, Murad R, Offermanns S, Metzger D, Chambon P, Widgerow AD, Tuan TL, Mortazavi A, Gupta RK, Hamilton BA, Millar SE, Seale P, Pear WS, Lazar MA, Cotsarelis G. Regeneration of fat cells from myofibroblasts during wound healing. Science. 2017 Feb 17;355(6326):748–752. PMCID: PMC5464786.

SanMiguel AJ, Meisel JS, Horwinski J, Zheng Q, Grice EA. Topical Antimicrobial Treatments Can Elicit Shifts to Resident Skin Bacterial Communities and Reduce Colonization by Staphylococcus aureus Competitors. Antimicrob Agents Chemother. 2017;61(9). PMCID: PMC5571303.

Sinnamon AJ, Neuwirth MG, Yalamanchi P, Gimotty P, Elder DE, Xu X, Kelz RR, Roses RE, Chu EY, Ming ME, Fraker DL, Karakousis GC. Association Between Patient Age and Lymph Node Positivity in Thin Melanoma. JAMA Dermatol. 2017 01;153(9):866–873. PMCID: PMC5710422.

Takeshita J, Grewal S, Langan SM, Mehta NN, Ogdie A, Van Voorhees AS, Gelfand JM. Psoriasis and comorbid diseases: Epidemiology. J Am Acad Dermatol. 2017 Mar;76(3):377–390. PMCID: PMC5731650.

Takeshita J, Grewal S, Langan SM, Mehta NN, Ogdie A, Van Voorhees AS, Gelfand JM. Psoriasis and comorbid diseases: Implications for management. J Am Acad Dermatol. 2017 Mar;76(3):393–403. PMCID: PMC5839668.

Wan J, Mitra N, Hoffstad OJ, Gelfand JM, Yan AC, Margolis DJ. Variations in risk of asthma and seasonal allergies between early- and late-onset pediatric atopic dermatitis: A cohort study. J Am Acad Dermatol. 2017 Oct;77(4):634–640. PMCID: PMC5653257.

Wang R, Cao XJ, Kulej K, Liu W, Ma T, MacDonald M, Chiang CM, Garcia BA, You J. Uncovering BRD4 hyperphosphorylation associated with cellular transformation in NUT midline carcinoma. Proc Natl Acad Sci USA. 2017 Jul 3;114(27):E5352–E5361. PMCID: PMC5502625.

Xu M, Horrell J, Snitow M, Cui J, Gochnauer H, Syrett CM, Kallish S, Seykora JT, Liu F, Gaillard D, Katz JP, Kaestner KH, Levin B, Mansfield C, Douglas JE, Cowart BJ, Tordoff M, Liu F, Zhu X, Barlow LA, Rubin AI, McGrath JA, Morrisey EE, Chu EY, Millar SE. WNT10A mutation causes ectodermal dysplasia by impairing progenitor cell proliferation and KLF4-mediated differentiation. Nat Commun. 2017 Jun 7;8:15397. PMCID: PMC5467248.

Yang Y, Carstens RP. Alternative splicing regulates distinct subcellular localization of Epithelial splicing regulatory protein 1 (Esrp1) isoforms. Sci Rep. 2017 Jun 20;7(1):3848–3. PMCID: PMC5478600.

2016

Taylor LA, O’Day C, Dentchev T, Hood K, Chu EY, Ridky TW, Seykora JT. p15 Expression Differentiates Nevus from Melanoma. Am J Pathol. 2016 Dec 1;186(12):3094–3099. PMCID: PMC5225287.