Core A

Cutaneous Phenomics And Transcriptomics (CPAT)

The role of the Cutaneous Phenomics and Transcriptomics Core (CPAT) is to provide services and training for the molecular characterization and histopathologic analysis of skin samples. Next Generation Sequencing (NGS) technologies for genomic and transcriptomic analysis, and advanced in-vivo imaging systems, are underpinned by expertise in skin immunohistotechnology and pathology. Translation of basic research findings to the clinic are enabled by an extensive archive of human skin disease and control samples.

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Skin tissue processing, microtomy, and staining (FFPE)
Archived human skin specimens (normal and diseased)
Immunostaining and cryosections
Laser Capture Microdissection (LCM)
RNAscope in situ hybridization
Skin barrier testing (TEWL, pH, and corneometry) - COMING IN AUGUST 2022!
Skin single cell suspension and library generation for scRNA-seq - COMING SOON
Intravital imaging (Two-photon microscopy and macrofluoresence) - COMING SOON