SBDRC Pilot & Feasibility Grant Program
2025 Application Instructions
Proposals will be accepted from University of Pennsylvania investigators that are:
- New/junior faculty investigators (defined as those who have not had R01 or equivalent funding) who
propose innovative skin research projects; - Faculty investigators proposing collaborative skin research projects that span multiple disciplines and/or the basic-translational-clinical research spectrum;
- Established investigators outside the field of skin research who want to apply their expertise to this area and/or collaborate with skin researchers;
- For Trainee Mini-grants: Postdoctoral scientists (MD, PhD, or MD/PhD) who are pursuing research projects that will allow them to transition to an independent faculty position incorporating skin research.
- For CCSD P&F Grants: Faculty at the rank of Assistant, Associate, or Full Professor proposing studies that develop and/or apply rigorous epidemiological, statistical, and/or informatics approaches to defining skin disease etiology and natural history, improving dermatology clinical practice, and community-based or population-based cutaneous health. Learn more about CCSD at: https://dermatology.upenn.edu/ccsd/ccsd_about/
All applications should include the following elements, and be submitted using the online application by August, 29 2025:
- Grant title
- Statement of investigator’s eligibility, including relevance of the application to scientific research areas supported by NIAMS (required)
- Brief summary of proposed use of SBDRC cores
- Specific Aims (1 page)
- Research Strategy (2 pages) in NIH format with Significance, Innovation, and Approach sections
- References
- Protection of Human Subjects, Data Safety Monitoring Plan, PHS Inclusion Enrollment Report, Inclusion of Women and Minorities, Inclusion Across the Lifespan (if applicable)
- Vertebrate Animals (if applicable)
- Letters of Support (optional for full grants; mentor letter required for Trainee Mini-grants)
- Authentication of Key Biological and/or Chemical Resources
- Resource Sharing Plan(s) for Data, Model Organisms, Genomic Data (if relevant)
- Select Agent Research (if applicable)
- Budget using NIH budget page PHS 398/FP4. Include personnel and budget justification.
- Please note that indirect costs and PI salary support are not allowable
- NIH Biosketch, latest format
- Follow NIH formatting guidelines, including acceptable fonts in black type and 0.5” page margins
- Note: Trainee Mini-grants will also require a letter of support from the applicant’s mentor
Evaluation
Proposals are reviewed using the updated 3-factor framework from NIH and consideration for the following additional criteria:
- Biological or clinical relevance of the project to skin biology and/or skin diseases within the scientific programs supported by NIAMS (please note, research on pre-cancerous lesions or the early stages of malignant transformation is acceptable, but not research solely focused on skin cancer);
- Use of one or more of the SBDRC Cores (required for SBDRC grant applications);
- Collaborative and/or multi-disciplinary aspects of project;
- Feasibility of supporting future external grant proposals;
- For Trainee Mini-grants: feasibility of supporting future transition to an independent research faculty position
- For CCSD P&F Grants: Additional criteria include 1) potential for results to be translated into improvements in skin health for patients and populations; 2) applications that include a PI or Co-PI with a strong record of leading epidemiological-based research in the field of dermatology will be prioritized.
Investigators receiving Penn SBDRC P&F grants will be required to:
- Provide IACUC and IRB protocol approvals before funding start date
- Submit a 1-page interim progress report and final report
- Present P&F-generated data at the Penn SBDRC Scientific Symposium (held annually in March)
- Provide annual updates on resulting grants and publications
- Participate in future SBDRC P&F Study Sections to evaluate applications
Questions regarding application submission can be directed to SBDRC@pennmedicine.upenn.edu.